Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484195 | 0.91 | ACHE (0.68) | ACHEKMT2AMEN1RAB9A | |
| SCHEMBL10640944 | 0.80 | KDM4E (0.53) | KMT2AMEN1 | |
| SCHEMBL4002090 | 0.78 | MEN1 (0.66) | ACHEKMT2AUSP2HSD17B10MEN1 | |
| SCHEMBL6404984 | 0.77 | MEN1 (0.62) | KMT2AUSP2MEN1GNAI3CHRM2 | |
| SCHEMBL5536939 | 0.77 | MEN1 (0.48) | ACHEKMT2AUSP2HSD17B10MEN1 | |
| SCHEMBL9830457 | 0.75 | TACR1 (0.56) | ACHEKMT2AUSP2MEN1GNAI3 | |
| SCHEMBL12939972 | 0.75 | KDM4E (0.51) | ACHEKMT2AUSP2HSD17B10MEN1 | |
| SCHEMBL8565231 | 0.75 | MEN1 (0.52) | ACHEKMT2AUSP2HSD17B10MEN1 | |
| SCHEMBL8565227 | 0.75 | MEN1 (0.52) | ACHEKMT2AUSP2HSD17B10MEN1 | |
| SCHEMBL3422052 | 0.74 | USP2 (0.58) | KMT2AUSP2HSD17B10MEN1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251846-A4 | C-4 CARBONATE TAXANES | BRISTOL MYERS SQUIBB CO (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1251846-A1 | C-4 CARBONATE TAXANES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001056565-A1 | C-4 CARBONATE TAXANES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |