Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22330321 | 0.84 | FKBP1A (0.49) | KMT2AALDH1A1 | |
| SCHEMBL10341462 | 0.75 | KMT2A (0.52) | HPGDKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13484174 | 0.75 | HPGD (0.47) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL22593164 | 0.74 | ALDH1A1 (0.56) | HPGDTSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6202791 | 0.74 | TSHR (0.58) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL9766998 | 0.73 | HPGD (0.46) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL1920902 | 0.72 | TSHR (0.45) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL3201676 | 0.72 | DPP4 (0.50) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL3185962 | 0.72 | DPP4 (0.50) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL3201687 | 0.72 | DPP4 (0.50) | HPGDTSHRKMT2AMEN1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251846-A4 | C-4 CARBONATE TAXANES | BRISTOL MYERS SQUIBB CO (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1251846-A1 | C-4 CARBONATE TAXANES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001056565-A1 | C-4 CARBONATE TAXANES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |