Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766998 | 0.85 | HPGD (0.46) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL3201676 | 0.83 | DPP4 (0.50) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL3201687 | 0.83 | DPP4 (0.50) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL27623771 | 0.83 | BRD4 (0.47) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL3185962 | 0.83 | DPP4 (0.50) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL9803156 | 0.81 | HPGD (0.43) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL3179986 | 0.81 | CCKBR (0.52) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL9803167 | 0.81 | HPGD (0.43) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL9802568 | 0.81 | HPGD (0.43) | HPGDTSHRKMT2AMEN1GRM2 | |
| SCHEMBL9767456 | 0.81 | HPGD (0.43) | HPGDTSHRKMT2AMEN1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41149-E1 | Stereoisomerically pure 7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-6-fluoro-1-[(1R,2S)-2-fluoro-1-cyclopropyl]-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid or a pharmaceutically acceptable salt thereof; antibacterial agents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-02-23 | — | — | US | disclosed |