Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558066 | 0.82 | GPR35 (0.59) | GPR35ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL27880083 | 0.78 | GPR35 (0.50) | GPR35ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL6186321 | 0.76 | ALDH1A1 (0.55) | GPR35ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL6186665 | 0.76 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TDP1TSHRHPGD | |
| SCHEMBL20535866 | 0.74 | ALDH1A1 (0.53) | GPR35ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL8654568 | 0.74 | GPR35 (0.71) | GPR35ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL22637083 | 0.73 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TDP1TSHRALOX15 | |
| SCHEMBL7209289 | 0.73 | ALDH1A1 (0.47) | GPR35ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL27916755 | 0.73 | TDP1 (0.47) | ALDH1A1CYP3A4TDP1TSHRALOX15 | |
| SCHEMBL2837407 | 0.73 | ALDH1A1 (0.55) | GPR35ALDH1A1CYP3A4TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617315-B1 | Sugar-substituted benzimidazole derivatives are used for the treatment or prophylaxis of restenosis, particularly following angioplasty | CHAMBERLAIN STANLEY DAWES (US) | 2003-09-09 | — | — | US | disclosed |