Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.47 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17024386 | 1.00 | MEN1 (0.61) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL17033274 | 0.99 | DNM1 (0.60) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL4203252 | 0.94 | MEN1 (0.63) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL17024373 | 0.93 | MEN1 (0.56) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL4205679 | 0.92 | DNM1 (0.62) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL17024382 | 0.92 | MEN1 (0.52) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL17033267 | 0.92 | DNM1 (0.52) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL7213507 | 0.92 | DNM1 (0.52) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL17033272 | 0.91 | DNM1 (0.55) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL17024381 | 0.91 | MGLL (0.52) | MEN1KMT2AMAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030224280-A1 | Process for lowering charge/mass ratio of toner particles having controlled morphology and containing quaternary ammonium tetraphenylborate charge control agents | HEIDELBERG DIGITAL L.L.C. | 2003-12-04 | — | — | US | disclosed |
| US-20030008227-A1 | Method for forming toner particles having controlled morphology and containing quaternary ammonium tetraphenylborate charge control agents | EASTMAN KODAK COMPANY | 2003-01-09 | — | — | US | disclosed |
| US-6416921-B1 | FORMING NON-SPHERICAL TONER PARTICLES USING LIMITED COALESCENSE; IMPROVED TRANSFER AND CLEANING EFFICIENCY | HEIDELBERG DIGITAL L.L.C. | 2002-07-09 | — | — | US | disclosed |