SCHEMBL7209721

SCHEMBL7209721

CO[Si](OC)(N1CCC(C)CC1)N1CCC(C)CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHGDH O43175 1/20 0.37
MGLL Q99685 1/20 0.37
ALDH1A1 P00352 7/20 0.34
NPC1 O15118 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TSHR P16473 3/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 4/20 0.32
GAA P10253 2/20 0.32
MAPT P10636 2/20 0.32
PTPN7 P35236 1/20 0.32
DUSP3 P51452 1/20 0.32
POLB P06746 4/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
ACHE P22303 2/20 0.31
CARM1 Q86X55 1/20 0.31
PRMT6 Q96LA8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14460065 0.82 ACHE (0.30) ACHE
SCHEMBL8073767 0.80 CARM1 (0.35) PHGDHMGLLALDH1A1NPC1MEN1
SCHEMBL8069006 0.73 MEN1 (0.33) ALDH1A1MEN1KMT2AHPGDPOLB
SCHEMBL7615563 0.73
SCHEMBL203745 0.73 MEN1 (0.30) MEN1KMT2ARECQL
SCHEMBL14460038 0.71
SCHEMBL11873117 0.70 SMN1; SMN2 (0.39) PHGDHMGLLALDH1A1NPC1MEN1
SCHEMBL5611439 0.70 MEN1 (0.33) MEN1KMT2ARECQL
SCHEMBL9195641 0.70 ACHE (0.37) POLBACHE
SCHEMBL7621896 0.69 POLB (0.38) ALDH1A1MEN1KMT2ATSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0841348-B1 Process for polymerization of alpha-olefin, a poly-alpha-olefin prepared thereby, and anaminosilane compound usable as the constituent of catalyst for the process MITSUI CHEMICALS INC (JP) 2003-07-02 EP disclosed
US-6376628-B1 USING COORDINATION POLYMERIZATION CATALYST GRAND POLYMER CO., LTD. (JP) 2002-04-23 US disclosed
US-6165930-A Organosilane compounds MONTELL NORTH AMERICA INC. (US) 2000-12-26 US disclosed
EP-0959083-A1 Process for polymerization of alpha-olefin and alpha-olefin polymer Grand Polymer Co., Ltd. (JP) 1999-11-24 EP disclosed
EP-0841348-A2 Process for polymerization of alpha-olefin, a poly-alpha-olefin prepared thereby, and anaminosilane compound usable as the constituent of catalyst for the process Grand Polymer Co., Ltd. (JP) 1998-05-13 EP disclosed
EP-0410443-B1 Organosilane compounds HIMONT INC (US) 1995-01-11 EP disclosed
US-5166340-A Polymerization catalysts, coordination catalysts for olefin polymerization HIMONT INCORPORATED (US) 1992-11-24 US disclosed
EP-0410443-A1 Organosilane compounds MONTELL NORTH AMERICA INC. (US) 1991-01-30 EP disclosed