SCHEMBL8073767

SCHEMBL8073767

CO[Si](OC)(OC)N1CCC(C)CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.35
PRMT6 Q96LA8 1/20 0.35
PRMT1 Q99873 1/20 0.35
PRMT8 Q9NR22 1/20 0.35
ALDH1A1 P00352 4/20 0.32
TSHR P16473 3/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.32
PKM P14618 1/20 0.32
KMT2A Q03164 1/20 0.32
PHGDH O43175 1/20 0.32
MGLL Q99685 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ACHE P22303 1/20 0.31
NPC1 O15118 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7209721 0.80 PHGDH (0.37) CARM1PRMT6PRMT1PRMT8ALDH1A1
SCHEMBL477697 0.78
SCHEMBL7615563 0.73
SCHEMBL27516073 0.70 MEN1 (0.33) MEN1KMT2A
SCHEMBL11873117 0.70 SMN1; SMN2 (0.39) CARM1PRMT6PRMT1PRMT8ALDH1A1
SCHEMBL9195641 0.70 ACHE (0.37) POLBACHE
SCHEMBL7621896 0.69 POLB (0.38) ALDH1A1TSHRL3MBTL1MEN1KMT2A
SCHEMBL8075305 0.68 HPGD (0.33) ALDH1A1TSHRL3MBTL1NPC1HPGD
SCHEMBL26965073 0.67 KMT2A (0.34) ALDH1A1TSHRKMT2AMGLLSMN1; SMN2
SCHEMBL27902513 0.67 ADRB1 (0.33) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6165930-A Organosilane compounds MONTELL NORTH AMERICA INC. (US) 2000-12-26 US disclosed
EP-0410443-B1 Organosilane compounds HIMONT INC (US) 1995-01-11 EP disclosed
US-5166340-A Polymerization catalysts, coordination catalysts for olefin polymerization HIMONT INCORPORATED (US) 1992-11-24 US disclosed
EP-0410443-A1 Organosilane compounds MONTELL NORTH AMERICA INC. (US) 1991-01-30 EP disclosed