Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209799 | 1.00 | L3MBTL1 (0.52) | L3MBTL1TACR2KMT2ACAPN1MEN1 | |
| Hydrochloric Acid SCHEMBL8205863 | 0.91 | L3MBTL1 (0.49) | L3MBTL1KMT2ACAPN1MEN1POLB | |
| SCHEMBL7204793 | 0.86 | KDM4E (0.49) | L3MBTL1KMT2AMEN1 | |
| SCHEMBL7206727 | 0.86 | L3MBTL1 (0.59) | L3MBTL1CAPN1POLBCHRNB2CHRNB4 | |
| SCHEMBL8349149 | 0.86 | L3MBTL1 (0.59) | L3MBTL1CAPN1POLBCHRNB2CHRNB4 | |
| SCHEMBL7206720 | 0.86 | L3MBTL1 (0.59) | L3MBTL1CAPN1POLBCHRNB2CHRNB4 | |
| SCHEMBL7205257 | 0.83 | MMP9 (0.50) | KMT2ACAPN1MEN1F13A1TGM2 | |
| SCHEMBL7205260 | 0.83 | MMP9 (0.50) | KMT2ACAPN1MEN1F13A1TGM2 | |
| SCHEMBL7204787 | 0.82 | L3MBTL1 (0.43) | L3MBTL1TACR2CAPN1POLB | |
| Hydrochloric Acid SCHEMBL7205771 | 0.82 | KMT2A (0.47) | KMT2ACAPN1MEN1F13A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6110967-A | USEFUL AS AGENTS FOR PREVENTING AND TREATING METABOLIC OSTEOPATHY SUCH AS OSTEOPOROSIS, HYPERCALCEMIA AND BONE METASTASIS OF CANCER BECAUSE THEY SPECIFICALLY INHIBITS CATHEPSIN L AND ITS FAMILY ENZYMES TO INHIBIT BONE RESORPTION | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0921122-A1 | NOVEL EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-06-09 | — | — | EP | disclosed |