Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | TPO | P07202 | 1/20 | 0.43 |
| ▸ | TRAP1 | Q12931 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TYMP | P19971 | 2/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209444 | 0.79 | TLR7 (0.38) | KMT2AMEN1TLR7CDK9DYRK1A | |
| SCHEMBL5732110 | 0.74 | ADORA2A (0.53) | ALDH1A1HIF1A | |
| SCHEMBL7209500 | 0.73 | ALDH1A1 (0.45) | TLR7CDK9DYRK1ADYRK2ALDH1A1 | |
| SCHEMBL5730393 | 0.71 | TLR7 (0.55) | TLR7 | |
| SCHEMBL7210390 | 0.69 | TLR7 (0.60) | TLR7 | |
| SCHEMBL7208352 | 0.68 | TLR7 (0.41) | TLR7 | |
| SCHEMBL2060319 | 0.68 | TLR7 (0.41) | KMT2ATLR7ALDH1A1KDM4EHPGD | |
| SCHEMBL7209290 | 0.67 | TLR7 (0.40) | KMT2ATLR7ALDH1A1KDM4EGLA | |
| SCHEMBL2060321 | 0.65 | ADORA2A (0.46) | TLR7ALDH1A1KDM4EGLAGAA | |
| SCHEMBL7206699 | 0.65 | ALDH1A1 (0.40) | KMT2AMEN1TYMSCDK9DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |