Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208339 | 0.90 | ADORA3 (0.48) | ALDH1A1TLR7NPC1RAB9AMAPK1 | |
| SCHEMBL7205773 | 0.90 | TLR7 (0.48) | CTSBALDH1A1TLR7KMT2ATP53 | |
| SCHEMBL10309752 | 0.89 | RAB9A (0.45) | ALDH1A1HPGDTLR7TP53NPC1 | |
| SCHEMBL7210357 | 0.87 | DRD2 (0.46) | CTSBALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL2060463 | 0.86 | DRD2 (0.48) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL2060411 | 0.86 | TP53 (0.53) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL2060547 | 0.84 | DRD2 (0.46) | HPGDTLR7KMT2ATP53ADORA3 | |
| SCHEMBL2060370 | 0.84 | ADORA3 (0.43) | ALDH1A1TP53NPC1RAB9AMAPK1 | |
| SCHEMBL7205100 | 0.84 | TLR7 (0.46) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL7209553 | 0.82 | TSHR (0.44) | ALDH1A1KDM4EGAAHPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |