Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210617 | 0.84 | PDE10A (0.43) | ATMCTSAALDH1A1GAAPDE1A | |
| SCHEMBL7774855 | 0.80 | KMT2A (0.38) | — | |
| SCHEMBL7588247 | 0.78 | MBNL1 (0.47) | MBNL1ATMCTSAALDH1A1MGAM | |
| SCHEMBL7869337 | 0.78 | MEN1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7869367 | 0.77 | MEN1 (0.30) | — | |
| SCHEMBL7118786 | 0.69 | PARP1 (0.43) | CTSAALDH1A1LMNATRPV3 | |
| SCHEMBL1598116 | 0.68 | PIK3CD (0.49) | MBNL1ATMMGAMGAASI | |
| Pamoic Acid SCHEMBL7877934 | 0.67 | POLB (0.52) | ALDH1A1 | |
| SCHEMBL12728134 | 0.66 | ATM (0.52) | MBNL1ATMMGAMGAASI | |
| SCHEMBL7115774 | 0.66 | PDE10A (0.40) | ATMCTSAALDH1A1GAAPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617336-B1 | Treatment of urinary incontinence, venous insufficiency, migraine or gastrointestinal disorders | SANOFI-SYNTHELABO (FR) | 2003-09-09 | — | — | US | claimed |
| CN-1413196-A | 2-Arylquinoline derivatives, preparation and therapeutic use thereof | SANOFI SYNTHELABO (FR) | 2003-04-23 | — | — | CN | claimed |
| EP-1240146-A1 | 2-ARYLQUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2002-09-18 | — | — | EP | claimed |
| WO-2001038310-A1 | 2-ARYLQUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2001-05-31 | — | — | WO | claimed |
| US-6617336-B1 | Treatment of urinary incontinence, venous insufficiency, migraine or gastrointestinal disorders | SANOFI-SYNTHELABO (FR) | 2003-09-09 | — | — | US | disclosed |
| CN-1413196-A | 2-Arylquinoline derivatives, preparation and therapeutic use thereof | SANOFI SYNTHELABO (FR) | 2003-04-23 | — | — | CN | disclosed |
| EP-1240146-A1 | 2-ARYLQUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001038310-A1 | 2-ARYLQUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2001-05-31 | — | — | WO | disclosed |