Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.67 |
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | DRD4 | P21917 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542239 | 0.85 | TDP1 (0.74) | NAAATDP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9364114 | 0.85 | POLB (0.65) | DRD2DRD4DRD3SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL7576777 | 0.84 | TDP1 (0.72) | NAAATDP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1002854 | 0.83 | NAAA (0.86) | NAAADRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL9628332 | 0.83 | NAAA (0.64) | NAAADRD2DRD4DRD3TDP1 | |
| SCHEMBL10872544 | 0.82 | TDP1 (0.60) | NAAADRD2DRD4DRD3TDP1 | |
| SCHEMBL10872304 | 0.82 | TDP1 (0.60) | NAAADRD2DRD4DRD3TDP1 | |
| SCHEMBL7215489 | 0.82 | THRA (0.63) | DRD2DRD4DRD3LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9774095 | 0.82 | NAAA (0.56) | NAAADRD2DRD4DRD3TDP1 | |
| SCHEMBL1003680 | 0.82 | NAAA (0.96) | NAAADRD2DRD4DRD3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663267-A | Subsituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use | UNIMED PHARMA SPOL SRO | 2010-03-03 | — | — | CN | claimed |
| CN-101663267-A | Subsituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use | UNIMED PHARMA SPOL SRO | 2010-03-03 | — | — | CN | disclosed |
| CN-1620421-A | Substituted alkyl diammine compound | EKOT RHEIN MEDICINE CO LTD (CH) | 2005-05-25 | — | — | CN | disclosed |
| EP-1335899-A2 | SUBSTITUTED ALKYLDIAMINES AS INHIBITORS OF PLASMEPSIN OR RELATED PROTEASES | Actelion Pharmaceuticals Ltd. (CH) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002038534-A2 | SUBSTITUTED ALKYLDIAMINES AS INHIBITORS OF PLASMEPSIN OR RELATED PROTEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-05-16 | — | — | WO | disclosed |