SCHEMBL7210971

SCHEMBL7210971

O=C(O)Nc1ccccc1C(=O)Nc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.66
RECQL P46063 1/20 0.66
HPGD P15428 2/20 0.65
ALDH1A1 P00352 3/20 0.63
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
KDM4E B2RXH2 2/20 0.61
LMNA P02545 2/20 0.61
TP53 P04637 1/20 0.61
HSD17B10 Q99714 1/20 0.61
POLB P06746 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
CYP2C9 P11712 2/20 0.58
METAP2 P50579 1/20 0.58
CYP3A4 P08684 1/20 0.58
ALOX12 P18054 1/20 0.58
CHRNB2 P17787 1/20 0.58
CHRNB4 P30926 1/20 0.58
CHRNA3 P32297 1/20 0.58
CHRNA4 P43681 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31690953 0.87 HTT (0.64) HTTRECQLHPGDALDH1A1MEN1
SCHEMBL328588 0.85 ALDH1A1 (0.82) HTTRECQLHPGDALDH1A1MEN1
SCHEMBL27134473 0.85 KMT2A (0.77) HTTRECQLHPGDALDH1A1MEN1
SCHEMBL14855627 0.85 POLB (0.79) HTTRECQLMEN1KMT2AKDM4E
SCHEMBL11002858 0.84 HDAC3 (0.64) HTTRECQLHPGDALDH1A1MEN1
SCHEMBL437231 0.83 ALDH1A1 (0.87) HTTHPGDALDH1A1MEN1KMT2A
SCHEMBL9189162 0.83 MEN1 (0.64) HTTRECQLHPGDALDH1A1MEN1
SCHEMBL27471728 0.82 MEN1 (0.74) HTTRECQLMEN1KMT2ALMNA
SCHEMBL11266257 0.81 ALDH1A1 (0.83) HTTHPGDALDH1A1MEN1KMT2A
SCHEMBL11266259 0.81 ALDH1A1 (0.83) HTTHPGDALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023785-B1 QUINOXALINYLOXYPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES ICI AUSTRALIA LIMITED (AU) 1985-04-03 EP claimed
EP-1073513-B1 IMPROVED EXTRUSION PROCESS BASF CORP (US) 2003-08-27 EP disclosed
US-6273929-B1 Extrusion process BASF CORPORATION 2001-08-14 US disclosed
US-5622658-A MIXING GRANULES; EXTRUSING MIXTURE; ROLLING TO BREAK GRANULES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1997-04-22 US disclosed
US-5443764-A Water-dispersible granules ICI AUSTRALIA OPERATIONS PROPIETARY LIMITED (AU) 1995-08-22 US disclosed
EP-0321527-B1 WATER DISPERSIBLE GRANULES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1992-08-12 EP disclosed
EP-0321527-A4 WATER DISPERSIBLE GRANULES. ICI AUSTRALIA OPERATIONS (AU) 1989-07-24 EP disclosed
EP-0321527-A1 WATER DISPERSIBLE GRANULES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1989-06-28 EP disclosed
WO-1989000079-A1 WATER DISPERSIBLE GRANULES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1989-01-12 WO disclosed