⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486621 | 0.91 | TET2 (0.33) | — | |
| SCHEMBL262088 | 0.90 | TSHR (0.32) | — | |
| SCHEMBL9718039 | 0.84 | ALDH1A1 (0.40) | — | |
| SCHEMBL475008 | 0.83 | TET2 (0.31) | — | |
| SCHEMBL7171781 | 0.81 | EPHX1 (0.33) | — | |
| SCHEMBL2121048 | 0.79 | TDP1 (0.31) | — | |
| SCHEMBL184269 | 0.79 | ALOX15 (0.31) | — | |
| SCHEMBL3748664 | 0.77 | TET2 (0.38) | — | |
| SCHEMBL28556062 | 0.76 | FFAR3 (0.44) | — | |
| SCHEMBL9632367 | 0.76 | CHRM1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9175242-B2 | Fluid having improved lubricity properties | EVONIK ROHMAX ADDITIVES GMBH (DE) | 2015-11-03 | — | — | US | disclosed |
| US-20140206823-A1 | METHOD FOR REDUCING THE HALOGEN CONTENT OF A POLYMER | EVONIK OIL ADDITIVES GMBH (DE) | 2014-07-24 | — | — | US | disclosed |
| US-20120053100-A1 | FLUID HAVING IMPROVED LUBRICITY PROPERTIES | EVONIK ROHMAX ADDITIVES GMBH (DE) | 2012-03-01 | — | — | US | disclosed |