Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628258 | 0.86 | CA1 (0.46) | TSHRALDH1A1CA1CA2CA5A | |
| SCHEMBL29197463 | 0.78 | ALDH1A1 (0.33) | TSHRALDH1A1CA1CA2CA5A | |
| SCHEMBL9016955 | 0.78 | ALDH1A1 (0.33) | TSHRALDH1A1CA1CA2CA5A | |
| SCHEMBL8854169 | 0.76 | KCNN4 (0.41) | TSHRALDH1A1CA1CA2CA5A | |
| SCHEMBL7191759 | 0.74 | TAS2R14 (0.42) | ALDH1A1CA1CA2CA5ACA9 | |
| SCHEMBL11620888 | 0.74 | CA1 (0.43) | TSHRALDH1A1CA1CA2CA5A | |
| SCHEMBL653490 | 0.74 | CA1 (0.32) | TSHRALDH1A1CA1CA2CA5A | |
| SCHEMBL6860810 | 0.74 | CA1 (0.54) | TSHRALDH1A1CA1CA2CA5A | |
| SCHEMBL9723026 | 0.73 | ALDH1A1 (0.65) | TSHRALDH1A1CA1CA2CA5A | |
| SCHEMBL4949544 | 0.73 | ALDH1A1 (0.32) | ALDH1A1CA1CA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620468-B2 | For use in liquid-crystal and electro-optical display elements | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2003-09-16 | — | — | US | disclosed |
| US-20020130300-A1 | For use in liquid-crystal and electro-optical display elements | MERCK GMBH (DE) | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020130300-A1 | For use in liquid-crystal and electro-optical display elements | CXCR1, ZYX, CXCR2 | TSHR 2495/4885ALDH1A1 509/4885CA1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.