Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | SGK1 | O00141 | 5/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212972 | 0.88 | ACLY (0.53) | ACLYCA1CA2CA7CA9 | |
| Propane SCHEMBL7213006 | 0.83 | CA1 (0.49) | FFAR1FFAR4ACLYBRD4CA1 | |
| SCHEMBL7213002 | 0.78 | ACLY (0.49) | FFAR1FFAR4ACLYBRD4CA1 | |
| SCHEMBL7208101 | 0.75 | PRMT1 (0.62) | FFAR1FFAR4CA1CA2CA9 | |
| SCHEMBL95834 | 0.74 | BRD4 (0.51) | BRD4CA1CA2CA7CA9 | |
| SCHEMBL13629290 | 0.74 | BRD4 (0.52) | BRD4SGK1HTR6PFKFB3ALDH1A1 | |
| SCHEMBL14018751 | 0.74 | ALDH1A1 (0.63) | ACLYBRD4CA1CA2SGK1 | |
| SCHEMBL13629339 | 0.73 | BRD4 (0.51) | BRD4SGK1TP53HTR6PFKFB3 | |
| SCHEMBL4445364 | 0.72 | KDM4E (0.58) | GRIN1KCNH2GRIN2BADRB2ADRB1 | |
| SCHEMBL7931494 | 0.72 | L3MBTL1 (0.65) | CA1CA2KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152857-C | Phenylsulfonamide-phenylethylamines useful as dopamine receptors | �������Ŷ���Լ��������˾ | 2004-06-09 | — | — | CN | claimed |
| EP-1077935-B1 | PHENYLSULFONAMIDE-PHENYLETHYLAMINES USEFUL AS DOPAMINE RECEPTORS | UPJOHN CO (US) | 2003-10-29 | — | — | EP | claimed |
| CN-1297431-A | Phenylsulfonamide-phenylethylamines useful as dopamine receptors | UPJOHN CO (US) | 2001-05-30 | — | — | CN | claimed |
| EP-1077935-A1 | PHENYLSULFONAMIDE-PHENYLETHYLAMINES USEFUL AS DOPAMINE RECEPTORS | PHARMACIA & UPJOHN COMPANY (US) | 2001-02-28 | — | — | EP | claimed |
| US-6103766-A | SUBSTITUTED OR UNSUBSTITUTED PHENYLSULFONAMIDE-PHENYLAMINE DERIVATIVES USEFUL FOR TREATING THE DISORDERS RELATED TO CENTRAL NERVOUS SYSTEM | PHARMACIA & UPJOHN COMPANY (US) | 2000-08-15 | — | — | US | claimed |
| WO-1999058499-A1 | PHENYLSULFONAMIDE-PHENYLETHYLAMINES USEFUL AS DOPAMINE RECEPTORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-11-18 | — | — | WO | claimed |
| EP-1077935-B1 | PHENYLSULFONAMIDE-PHENYLETHYLAMINES USEFUL AS DOPAMINE RECEPTORS | UPJOHN CO (US) | 2003-10-29 | — | — | EP | disclosed |
| EP-1077935-A1 | PHENYLSULFONAMIDE-PHENYLETHYLAMINES USEFUL AS DOPAMINE RECEPTORS | PHARMACIA & UPJOHN COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| US-6103766-A | SUBSTITUTED OR UNSUBSTITUTED PHENYLSULFONAMIDE-PHENYLAMINE DERIVATIVES USEFUL FOR TREATING THE DISORDERS RELATED TO CENTRAL NERVOUS SYSTEM | PHARMACIA & UPJOHN COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| WO-1999058499-A1 | PHENYLSULFONAMIDE-PHENYLETHYLAMINES USEFUL AS DOPAMINE RECEPTORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-11-18 | — | — | WO | disclosed |