Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 5/20 | 0.50 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042469 | 1.00 | OPRD1 (0.52) | OPRD1OPRM1OPRK1MMP2CTSL | |
| SCHEMBL6828134 | 1.00 | OPRD1 (0.52) | OPRD1OPRM1OPRK1MMP2CTSL | |
| SCHEMBL29590936 | 0.99 | OPRD1 (0.51) | OPRD1OPRM1OPRK1MMP2CTSL | |
| Hydrochloric Acid SCHEMBL30333426 | 0.99 | OPRD1 (0.51) | OPRD1OPRM1OPRK1MMP2CTSL | |
| SCHEMBL30939437 | 0.99 | OPRD1 (0.51) | OPRD1OPRM1OPRK1MMP2CTSL | |
| SCHEMBL29714770 | 0.99 | OPRD1 (0.51) | OPRD1OPRM1OPRK1MMP2CTSL | |
| SCHEMBL21437346 | 0.99 | OPRD1 (0.51) | OPRD1OPRM1OPRK1MMP2CTSL | |
| SCHEMBL30805357 | 0.95 | CTSL (0.51) | OPRD1OPRM1OPRK1MMP2CTSL | |
| SCHEMBL29385523 | 0.95 | CTSL (0.51) | OPRD1OPRM1OPRK1MMP2CTSL | |
| Trifluoroacetic Acid SCHEMBL23629875 | 0.94 | OPRD1 (0.47) | OPRD1OPRM1OPRK1MMP2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617456-B1 | Aminoalkoxy- or hydroxyalkoxy- camptothecin compound that can be bound to a polysaccharide having carboxyl groups via an amino acid or a peptide group; antitumor agents | TANABE SEIYAKU CO., LTD. (JP) | 2003-09-09 | — | — | US | claimed |