SCHEMBL6828134

SCHEMBL6828134

NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 5/20 0.52
▸ OPRM1 P35372 4/20 0.52
▸ OPRK1 P41145 1/20 0.52
▸ MMP2 P08253 1/20 0.51
▸ CTSL P07711 1/20 0.51
▸ CTSB P07858 1/20 0.51
▸ CTSS P25774 1/20 0.51
▸ MME P08473 5/20 0.50
▸ ACE P12821 3/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ HPGD P15428 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ ECE1 P42892 1/20 0.50
▸ BLM P54132 1/20 0.50
▸ NPEPPS P55786 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ QRFPR Q96P65 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7042469 1.00 OPRD1 (0.52) OPRD1OPRM1OPRK1MMP2CTSL
SCHEMBL7211697 1.00 OPRD1 (0.52) OPRD1OPRM1OPRK1MMP2CTSL
SCHEMBL29590936 0.99 OPRD1 (0.51) OPRD1OPRM1OPRK1MMP2CTSL
Hydrochloric Acid SCHEMBL30333426 0.99 OPRD1 (0.51) OPRD1OPRM1OPRK1MMP2CTSL
SCHEMBL30939437 0.99 OPRD1 (0.51) OPRD1OPRM1OPRK1MMP2CTSL
SCHEMBL29714770 0.99 OPRD1 (0.51) OPRD1OPRM1OPRK1MMP2CTSL
SCHEMBL21437346 0.99 OPRD1 (0.51) OPRD1OPRM1OPRK1MMP2CTSL
SCHEMBL30805357 0.95 CTSL (0.51) OPRD1OPRM1OPRK1MMP2CTSL
SCHEMBL29385523 0.95 CTSL (0.51) OPRD1OPRM1OPRK1MMP2CTSL
Trifluoroacetic Acid SCHEMBL23629875 0.94 OPRD1 (0.47) OPRD1OPRM1OPRK1MMP2CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748396-A1 PHARMACEUTICAL COMPOSITION CONTAINING ANTI-NECTIN4 ANTIBODY-DRUG CONJUGATE AND ANTI-PD-1 ANTIBODY AND USE THEREOF Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd. (CN) 2026-05-27 — — EP claimed
EP-4746921-A1 DRUG CONJUGATES OF IMIDAZOQUINOLINE AMINE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF Canwell Biotech Limited (CN) 2026-05-27 — — EP claimed
CN-122080121-A Linker and use thereof in ligand drug conjugates — 2026-05-26 — — CN claimed
WO-2026105061-A1 ANTIBODY-DRUG CONJUGATES THAT BIND CDCP1 AND USES THEREOF PHEON THERAPEUTICS LTD (GB) 2026-05-21 — — WO claimed
US-20260137794-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF SYSTIMMUNE INC (US) 2026-05-21 — — US claimed
US-20260115305-A1 LINKERS, CONJUGATES AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE SUZHOU CO LTD (CN) 2026-04-30 — — US claimed
EP-4732851-A1 LINKER, ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR Fudan University (CN) 2026-04-29 — — EP claimed
EP-4731673-A1 NECTIN-4 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES Eli Lilly and Company (US) 2026-04-29 — — EP claimed
US-20260102507-A1 CAMPTOTHECIN DERIVATIVE FOR TREATING OR PREVENTING CANCER AND ANTIBODY-DRUG CONJUGATE THEREOF CHENGDU BRILLIANT PHARMACEUTICAL CO LTD (CN) 2026-04-16 — — US claimed
EP-4725969-A1 ANTI-HER2 COMPLEMENTARY BISPECIFIC ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Latticon (Suzhou) Biopharmaceuticals Co., Ltd. (CN) 2026-04-15 — — EP claimed
US-6458347-B1 Drug complex ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-10-01 — — US claimed
CN-1073113-C Camptothecin derivative and preparation method and application thereof TANABE SEIYAKU CO (JP) 2001-10-17 — — CN claimed
EP-0781781-B1 Camptothecin derivatives TANABE SEIYAKU CO (JP) 2001-10-10 — — EP claimed
CN-1300733-A Comptothecin compounds and preparation thereof TANABE SEIYAKU CO (JP) 2001-06-27 — — CN claimed
US-5892043-A MIXTURE WITH POLYSACCHARIDE AND PEPTIDE; ANTITUMOR AGENT TANABE SEIYAKU CO., LTD. (JP) 1999-04-06 — — US claimed
EP-0757049-B1 Camptothecin derivatives TANABE SEIYAKU CO (JP) 1999-03-24 — — EP claimed
US-5837673-A ANTITUMOR AGENTS AND ANTICARCINOGENIC AGENTS TANABE SEIYAKU CO., LTD. (JP) 1998-11-17 — — US claimed
CN-1158334-A Camptothecin derivatives TANABE SEIYAKU CO (JP) 1997-09-03 — — CN claimed
EP-0781781-A2 Camptothecin derivatives TANABE SEIYAKU CO., LTD. (JP) 1997-07-02 — — EP claimed
EP-0757049-A1 Camptothecin derivatives TANABE SEIYAKU CO., LTD. (JP) 1997-02-05 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115305-A1 LINKERS, CONJUGATES AND APPLICATIONS THEREOF CLTB, DCLRE1A, FCGRT OPRD1 2720/4885OPRM1 2483/4885OPRK1 2885/4885
US-20260137794-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF CHEK1, ATR, MRE11 OPRD1 2627/4885OPRM1 3393/4885OPRK1 3381/4885
US-20260102507-A1 CAMPTOTHECIN DERIVATIVE FOR TREATING OR PREVENTING CANCER AND ANTIBODY-DRUG CONJUGATE THEREOF MALT1, FCGRT, CHN2 OPRD1 3056/4885OPRM1 933/4885OPRK1 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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