Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29783093 | 0.90 | L3MBTL1 (0.61) | EZH2MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL2908330 | 0.84 | EZH2 (0.89) | EZH2MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL9302824 | 0.81 | EZH2 (0.58) | EZH2MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL8738588 | 0.79 | EZH2 (1.00) | EZH2MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL6119822 | 0.77 | EZH2 (0.80) | EZH2MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL11484910 | 0.77 | EZH2 (0.56) | EZH2MEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL8738670 | 0.76 | EZH2 (0.74) | EZH2MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL6120593 | 0.76 | EZH2 (0.74) | EZH2MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL169747 | 0.76 | EZH2 (0.80) | EZH2MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL28197914 | 0.76 | EZH2 (0.57) | EZH2MEN1KMT2AL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608122-B1 | O-Hydroxyphenyl-s-triazines in combination with sterically hindered amines of the polyalkylpiperidine type | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-08-19 | — | — | US | disclosed |