SCHEMBL9302824

SCHEMBL9302824

C=CCC1(CC=C)CC(NC(=O)c2ccccc2)CC(CC=C)(CC=C)N1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EZH2 Q15910 9/20 0.58
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
POLB P06746 1/20 0.42
MCHR1 Q99705 1/20 0.41
GAA P10253 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
CARM1 Q86X55 1/20 0.41
PRMT6 Q96LA8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7211981 0.81 EZH2 (0.66) EZH2MEN1KMT2AL3MBTL1POLB
SCHEMBL2908330 0.78 EZH2 (0.89) EZH2MEN1KMT2AL3MBTL1POLB
SCHEMBL11491069 0.75 EZH2 (0.51) EZH2MEN1KMT2AL3MBTL1NPC1
SCHEMBL8738588 0.73 EZH2 (1.00) EZH2MEN1KMT2AL3MBTL1POLB
SCHEMBL28197914 0.72 EZH2 (0.57) EZH2MEN1KMT2AL3MBTL1NPC1
SCHEMBL29783093 0.71 L3MBTL1 (0.61) EZH2MEN1KMT2AL3MBTL1NPC1
SCHEMBL6119822 0.70 EZH2 (0.80) EZH2MEN1KMT2AL3MBTL1NPC1
SCHEMBL8738670 0.70 EZH2 (0.74) EZH2MEN1KMT2AL3MBTL1POLB
SCHEMBL8738163 0.70 EZH2 (0.74) EZH2MEN1KMT2AL3MBTL1POLB
SCHEMBL6120593 0.70 EZH2 (0.74) EZH2MEN1KMT2AL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8633265-B2 UV stabilization of isosorbide polycarbonates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-21 US disclosed
EP-2665775-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC Innovative Plastics IP B.V. (NL) 2013-11-27 EP disclosed
WO-2012098513-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-26 WO disclosed
US-20120184651-A1 UV Stabilization of Isosorbide Polycarbonates SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-07-19 US disclosed
US-RE34791-E Polymer bound hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1994-11-15 US disclosed
EP-0303987-B1 POLYMER BOUND HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-10-14 EP disclosed
US-4975489-A Heating an anhydride-containing polymer with a hydrazine derivative of a 2,2,6,6-tetramethyl-4-aminopiperidine in an inert solvent of by melt blending ATOCHEM NORTH AMERICA, INC. (US) 1990-12-04 US disclosed
US-4857595-A Polymer bound hindered amine light stabilizers PENNWALT CORPORATION (US) 1989-08-15 US disclosed
US-4824884-A Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers PENNWALT CORPORATION (US) 1989-04-25 US disclosed
EP-0303987-A2 Polymer bound hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303282-A2 Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed