SCHEMBL7212090

SCHEMBL7212090

CC(=O)OC1C[C@H](CO)O[C@@H]1n1cc(I)c(=O)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PYGM P11217 1/20 0.50
TK1 P04183 3/20 0.49
RNASE1 P07998 1/20 0.41
P2RY6 Q15077 4/20 0.40
P2RY14 Q15391 3/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
ALB P02768 1/20 0.40
POLB P06746 1/20 0.40
ADRA1A P35348 1/20 0.40
BLM P54132 1/20 0.40
TYMP P19971 4/20 0.38
BCHE P06276 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7212087 1.00 PYGM (0.50) PYGMTK1RNASE1P2RY6P2RY14
SCHEMBL2580677 0.90 PYGM (0.44) PYGMTK1RNASE1P2RY6P2RY14
SCHEMBL2580676 0.90 PYGM (0.44) PYGMTK1RNASE1P2RY6P2RY14
SCHEMBL2583581 0.87 PYGM (0.41) PYGMTK1RNASE1P2RY6P2RY14
SCHEMBL2581471 0.80 RNASE1 (0.45) TK1RNASE1ALDH1A1LMNAALB
SCHEMBL1566532 0.80 TK1 (0.67) PYGMTK1RNASE1LMNABLM
SCHEMBL12712226 0.80 TK1 (0.67) PYGMTK1RNASE1LMNABLM
SCHEMBL1566533 0.80 TK1 (0.67) PYGMTK1RNASE1LMNABLM
SCHEMBL2581474 0.80 RNASE1 (0.45) TK1RNASE1ALDH1A1LMNAALB
SCHEMBL13314169 0.80 TK1 (0.67) PYGMTK1RNASE1LMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785278-B1 METHOD FOR DETERMINING DNA NUCLEOTIDE SEQUENCE RIKAGAKU KENKYUSHO (JP) 2003-02-05 EP disclosed
US-6074824-A Method for determining DNA nucleotide sequence THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) 2000-06-13 US disclosed
EP-0785278-A1 METHOD OF DNA SEQUENCING THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) 1997-07-23 EP disclosed