Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 12/20 | 0.80 |
| ▸ | MMP8 | P22894 | 3/20 | 0.80 |
| ▸ | MMP1 | P03956 | 7/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076532 | 0.89 | MMP13 (1.00) | MMP13MMP8MMP1HTTNPSR1 | |
| SCHEMBL7208360 | 0.87 | MMP13 (0.90) | MMP13MMP8MMP1HTTNPSR1 | |
| SCHEMBL4195258 | 0.82 | MMP13 (0.66) | MMP13MMP8MMP1HTTNPSR1 | |
| SCHEMBL4183847 | 0.81 | MMP13 (0.64) | MMP13MMP8MMP1HTTNPSR1 | |
| SCHEMBL6379006 | 0.81 | MMP13 (0.64) | MMP13MMP8MMP1HTTNPSR1 | |
| SCHEMBL4190555 | 0.81 | HTT (0.67) | MMP13MMP8MMP1HTTNPSR1 | |
| SCHEMBL6708168 | 0.79 | PKM (0.64) | MMP13MMP8MMP1HTTNPSR1 | |
| SCHEMBL3250372 | 0.79 | PKM (0.64) | MMP13MMP8MMP1HTTNPSR1 | |
| SCHEMBL20054093 | 0.79 | MMP13 (0.72) | MMP13MMP8MMP1HTTNPSR1 | |
| Hydrochloric Acid SCHEMBL19259893 | 0.79 | MMP13 (0.62) | MMP13MMP8MMP1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939628-B1 | THIOL SULFONE METALLOPROTEASE INHIBITORS | MONSANTO CO (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6013649-A | BOND DISORDERS; AUTOIMMUNE DISEASES; ANTITUMOR AGENTS | MONSANTO COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0939628-A4 | THIOL SULFONE METALLOPROTEASE INHIBITORS | MONSANTO CO (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0939628-A1 | THIOL SULFONE METALLOPROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998003164-A1 | THIOL SULFONE METALLOPROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1998-01-29 | — | — | WO | disclosed |