Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204883 | 0.91 | LSS (0.43) | EPHX2LSSCA12CA9MAPK14 | |
| SCHEMBL7204634 | 0.91 | LSS (0.43) | EPHX2LSSCA12CA9MAPK14 | |
| SCHEMBL7208957 | 0.90 | EPHX2 (0.42) | EPHX2LSSCA12CA9MAPK14 | |
| SCHEMBL7203242 | 0.89 | EPHX2 (0.41) | EPHX2LSSCA12CA9MAPK14 | |
| SCHEMBL7210660 | 0.81 | KDM4E (0.40) | — | |
| SCHEMBL7205346 | 0.78 | SMYD3 (0.45) | EPHX2KDM5A | |
| SCHEMBL7210420 | 0.77 | ALDH1A1 (0.52) | EPHX2CA1 | |
| SCHEMBL7210414 | 0.77 | ALDH1A1 (0.52) | EPHX2CA1 | |
| SCHEMBL7209252 | 0.76 | MAPK14 (0.41) | LSSMAPK14KDM5A | |
| SCHEMBL7211489 | 0.75 | NAAA (0.45) | MAPK14HDAC6KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |