Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505133 | 0.83 | CYP4F2 (0.36) | CYP4F2CYP4A11 | |
| SCHEMBL6691583 | 0.77 | CYP4F2 (0.40) | CYP4F2CYP4A11 | |
| SCHEMBL6502656 | 0.77 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL6692896 | 0.76 | CYP4F2 (0.42) | CYP4F2CYP4A11 | |
| SCHEMBL27596099 | 0.72 | ACLY (0.42) | CYP4F2CYP4A11 | |
| SCHEMBL27578128 | 0.71 | ACLY (0.45) | CYP4F2CYP4A11 | |
| SCHEMBL6709910 | 0.70 | DGAT1 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL27596160 | 0.68 | ACACB (0.39) | CYP4F2CYP4A11 | |
| SCHEMBL6503462 | 0.65 | ACLY (0.47) | — | |
| SCHEMBL1245575 | 0.65 | CYP4F2 (0.46) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366024-A2 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002030882-A2 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |