Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284592 | 0.79 | OPRM1 (0.38) | KDM4EKCNH2 | |
| SCHEMBL3665848 | 0.76 | NPSR1 (0.35) | NPSR1USP2CYP3A4MEN1KMT2A | |
| SCHEMBL9762967 | 0.74 | — | — | |
| SCHEMBL845600 | 0.74 | — | — | |
| SCHEMBL845602 | 0.74 | — | — | |
| SCHEMBL10792890 | 0.73 | ALDH1A1 (0.34) | NPSR1USP2CYP3A4MEN1KMT2A | |
| SCHEMBL6286104 | 0.72 | ALDH1A1 (0.35) | KDM4ELMNAALDH1A1 | |
| SCHEMBL4309286 | 0.71 | GRIN2B (0.40) | USP2 | |
| SCHEMBL4437296 | 0.71 | GRIN2B (0.40) | USP2 | |
| SCHEMBL692636 | 0.71 | GRIN2B (0.40) | USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036966-A | Difluorinated tripeptides as HCV serine protease inhibitors | ENANTA PHARM INC | 2011-04-27 | — | — | CN | disclosed |
| CN-101977621-A | Fluorinated tripeptide hcv serine protease inhibitors | ENANTA PHARM INC | 2011-02-16 | — | — | CN | disclosed |
| US-6613738-B1 | Comprising 1,2-dihydroxy-homotyrosine, 4-hydroxyproline, threonine, glutamine, 3-,4-dihydroxymethylproline, 4,5-dihydroxyornithine and lipid | HMV CORPORATION | 2003-09-02 | — | — | US | disclosed |
| WO-2000009735-A1 | A CYCLIC LIPOPEPTIDE FROM CRYPTOSPORIOPSIS QUERCINA POSSESSING ANTIFUNGAL ACTIVITY | STROBEL GARY A (US) | 2000-02-24 | — | — | WO | disclosed |