Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 3/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357449 | 0.86 | LTA4H (0.54) | RENLTA4HGRNSORT1CTSK | |
| SCHEMBL8229720 | 0.83 | LTA4H (0.43) | RENLTA4HGRNSORT1CTSK | |
| SCHEMBL10710541 | 0.83 | LTA4H (0.40) | RENLTA4HGRNSORT1PYGL | |
| SCHEMBL13038056 | 0.83 | LTA4H (0.43) | RENLTA4HGRNSORT1CTSK | |
| SCHEMBL7401954 | 0.83 | CTSS (0.56) | RENCTSKCTSS | |
| SCHEMBL7311968 | 0.83 | CTSS (0.56) | RENCTSKCTSS | |
| SCHEMBL5847958 | 0.83 | CTSS (0.56) | RENCTSKCTSS | |
| SCHEMBL13134807 | 0.83 | CTSS (0.56) | RENCTSKCTSS | |
| SCHEMBL7872157 | 0.83 | CTSS (0.56) | RENCTSKCTSS | |
| SCHEMBL9819695 | 0.83 | CTSS (0.56) | RENCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934923-B1 | OPTICALLY ACTIVE ERYTHRO-3-AMINO-2-HYDROXYBUTYRIC ESTERS AND PROCESS FOR PREPARING SAID ESTERS | NIPPON KAYAKU KK (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6063955-A | OXIDIZING A THREO OR THREO-ERYTHRO-3-AMINO-2-HYDROXYBUTYRIC ACID ESTER, OPTICALLY ACTIVE AT 3-POSITION TO PRODUCE AN OPTICALLY ACTIVE 3-AMINO-2-OXOBUTYRIC ESTER, REDUCING ERYTHRO-SELECTIVELY CARBONYL GROUP AT 2-POSITION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0934923-A1 | OPTICALLY ACTIVE ERYTHRO-3-AMINO-2-HYDROXYBUTYRIC ESTERS AND PROCESS FOR PREPARING SAID ESTERS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | disclosed |