Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374272 | 0.93 | MMP8 (0.53) | MMP8MEN1NPC1KMT2APIN1 | |
| SCHEMBL10441680 | 0.86 | PDPK1 (0.53) | MEN1KMT2ATDP1HKDC1PDPK1 | |
| SCHEMBL11274961 | 0.84 | MMP8 (0.46) | MMP8MEN1NPC1KMT2APIN1 | |
| SCHEMBL4298901 | 0.82 | CPA1 (0.46) | MMP8MEN1NPC1KMT2APIN1 | |
| SCHEMBL4298905 | 0.82 | CPA1 (0.46) | MMP8MEN1NPC1KMT2APIN1 | |
| SCHEMBL16732233 | 0.82 | MMP8 (0.49) | MMP8MEN1NPC1KMT2APIN1 | |
| SCHEMBL15216694 | 0.81 | MMP8 (0.51) | MMP8MEN1NPC1KMT2APIN1 | |
| SCHEMBL7418448 | 0.81 | MMP8 (0.51) | MMP8MEN1NPC1KMT2APIN1 | |
| SCHEMBL28691890 | 0.81 | MMP8 (0.51) | MMP8MEN1NPC1KMT2APIN1 | |
| SCHEMBL5880392 | 0.81 | HKDC1 (0.47) | MEN1KMT2AHKDC1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613934-B1 | Enzymatic partial hydrolysis of a diester of malonic acid | DEGUSSA AG (DE) | 2003-09-02 | — | — | US | disclosed |