Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10441680 | 0.90 | PDPK1 (0.53) | HKDC1PDPK1LMNAHSD17B10SRC | |
| SCHEMBL6174681 | 0.83 | CYP3A4 (0.52) | HKDC1LMNAPOLBMEN1KMT2A | |
| SCHEMBL7434255 | 0.82 | ALPI (0.50) | PDPK1HSD17B10CYP2D6POLBMEN1 | |
| SCHEMBL28053724 | 0.81 | HKDC1 (0.47) | HKDC1PDPK1LMNAHSD17B10SRC | |
| SCHEMBL7212425 | 0.81 | MMP8 (0.50) | HKDC1PDPK1MEN1KMT2A | |
| SCHEMBL9208938 | 0.80 | ACP3 (0.38) | LMNAMEN1KMT2A | |
| SCHEMBL13962437 | 0.79 | HKDC1 (0.49) | HKDC1LMNAHSD17B10CYP2D6POLB | |
| SCHEMBL12777880 | 0.77 | HKDC1 (0.44) | HKDC1LMNAHSD17B10SRCCYP2D6 | |
| SCHEMBL4612358 | 0.77 | CYP2D6 (0.61) | HKDC1LMNAHSD17B10SRCCYP2D6 | |
| SCHEMBL4612061 | 0.77 | CYP2D6 (0.61) | HKDC1LMNAHSD17B10SRCCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141694-B2 | Enzymatic resolution of aryl and thio-substituted acids | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-11-28 | — | — | US | claimed |
| US-20040166534-A1 | Combinatorial library comprising pouches as packages for library members and method therefor | 3M INNOVATIVE PROPERTIES COMPANY | 2004-08-26 | — | — | US | disclosed |
| EP-1370353-A2 | COMBINATORIAL LIBRARY COMPRISING POUCHES AS PACKAGES FOR LIBRARY MEMBERS | 3M Innovative Properties Company (US) | 2003-12-17 | — | — | EP | disclosed |
| US-20020160527-A1 | Combinatorial library comprising pouches as packages for library members and method therefor | 3M INNOVATIVE PROPERTIES COMPANY | 2002-10-31 | — | — | US | disclosed |
| WO-2002068264-A2 | COMBINATORIAL LIBRARY COMPRISING POUCHES AS PACKAGES FOR LIBRARY MEMBERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
| US-5800897-A | Air freshener composition containing a fiber pad | EASTMAN CHEMICAL COMPANY (US) | 1998-09-01 | — | — | US | disclosed |
| WO-1997026926-A1 | AIR FRESHENER COMPOSITION CONTAINING A FIBER PAD | EASTMAN CHEMICAL COMPANY (US) | 1997-07-31 | — | — | WO | disclosed |