SCHEMBL7212581

SCHEMBL7212581

Cc1ccc(N(c2ccc(C)cc2)c2c3ccccc3c(-c3cccc4ccccc34)c3ccccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.41
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP2A6 P11509 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
TYMP P19971 1/20 0.34
GSK3B P49841 1/20 0.34
ADK P55263 1/20 0.34
FLT3 P36888 1/20 0.34
KMT2A Q03164 2/20 0.33
NISCH Q9Y2I1 1/20 0.33
ENPP3 O14638 1/20 0.33
ENPP1 P22413 1/20 0.33
MEN1 O00255 1/20 0.33
HTR2C P28335 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14461150 0.87 MEN1 (0.40) DHFRKDM4EALDH1A1CYP2A6TDP1
SCHEMBL14099720 0.85 DHFR (0.39) DHFRMAOAMAOBKDM4EALDH1A1
SCHEMBL14461158 0.84 CA12 (0.39) DHFRKDM4EALDH1A1TDP1TYMP
SCHEMBL12617689 0.84 HPGD (0.39) MAOAKDM4EALDH1A1TDP1RAB9A
SCHEMBL12617905 0.83 HPGD (0.38) MAOAMAOBALDH1A1TDP1RAB9A
SCHEMBL13222616 0.83 GPR84 (0.38) KDM4EALDH1A1CYP2A6TDP1RAB9A
SCHEMBL14336821 0.83 GPR84 (0.38) KDM4EALDH1A1CYP2A6TDP1RAB9A
SCHEMBL2540242 0.83 ALDH1A1 (0.39) KDM4EALDH1A1TDP1KMT2AMEN1
SCHEMBL15762770 0.82 DHFR (0.38) DHFRMAOAMAOBKDM4EALDH1A1
SCHEMBL15762789 0.82 DHFR (0.38) DHFRMAOAMAOBKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1191821-B1 Organic electroluminescent element and organic electroluminescent material used therefor KONICA CORP (JP) 2009-05-27 EP disclosed
US-6582837-B1 Device having one or more organic thin layers including luminescent layer between anode and cathode, wherein at least one layer contains selected compound or compounds; exhibits higher-luminance luminescence than conventional device NEC CORPORATION (JP) 2003-06-24 US disclosed