Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL7219396 | 0.88 | HSD17B10 (0.45) | HSD17B10TDP1TSHRHPGDHCAR2 | |
| 1,3-Butanediol SCHEMBL4329578 | 0.86 | HSD17B10 (0.47) | HSD17B10TDP1TSHRALDH1A1MAPT | |
| 1,3-Butanediol SCHEMBL659565 | 0.86 | LMNA (0.46) | HSD17B10TDP1TSHRLMNAALDH1A1 | |
| 1,3-Butanediol SCHEMBL3883350 | 0.86 | LMNA (0.46) | HSD17B10TDP1TSHRLMNAALDH1A1 | |
| Acrylic Acid SCHEMBL7212826 | 0.85 | THRB (0.42) | HSD17B10TDP1TSHRHPGDHCAR2 | |
| 1,3-Butanediol SCHEMBL20537096 | 0.84 | LMNA (0.40) | HSD17B10TSHRLMNAALDH1A1TP53 | |
| 1,3-Butanediol SCHEMBL873212 | 0.84 | HSD17B10 (0.56) | HSD17B10TDP1TSHRALDH1A1MAPT | |
| Methacrylic Acid SCHEMBL7214459 | 0.83 | HSD17B10 (0.41) | HSD17B10TDP1TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL7786724 | 0.82 | LMNA (0.50) | HSD17B10TSHRHPGDHCAR2LMNA | |
| Acrylic Acid SCHEMBL3641809 | 0.82 | LMNA (0.50) | HSD17B10TSHRHPGDHCAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624236-B1 | Sol-gel-condensable cyclosiloxane(meth) acrylates; dentistry | 3M ESPE AG (DE) | 2003-09-23 | — | — | US | disclosed |
| EP-1141094-B1 | CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS | 3M ESPE AG (DE) | 2002-07-24 | — | — | EP | disclosed |