Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.59 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032843 | 0.85 | PTGS2 (0.66) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL6152172 | 0.85 | CXCL8 (0.46) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL1032907 | 0.85 | PTGS2 (0.69) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3871928 | 0.80 | PTGS2 (0.65) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL17917294 | 0.80 | PTGS2 (0.85) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL17917316 | 0.79 | PTGS2 (0.65) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3869145 | 0.77 | PTGS2 (0.53) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL27773589 | 0.77 | PTGS2 (0.53) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL13633978 | 0.76 | PTGS2 (0.80) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3871688 | 0.76 | PTGS2 (0.60) | PTGS2ABCB11PTGS1PPARGNR1I3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003510303-A | — | — | 2003-03-18 | — | — | JP | claimed |
| EP-1216226-A2 | PROCESS FOR PHENYLACETIC ACID DERIVATIVES | Novartis AG (CH) | 2002-06-26 | — | — | EP | claimed |
| WO-2001023346-A2 | PROCESS FOR PHENYLACETIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2001-04-05 | — | — | WO | claimed |
| EP-1216226-A2 | PROCESS FOR PHENYLACETIC ACID DERIVATIVES | Novartis AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001023346-A2 | PROCESS FOR PHENYLACETIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2001-04-05 | — | — | WO | disclosed |