Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TYMP | P19971 | 4/20 | 0.39 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213472 | 0.81 | UPP1 (0.47) | UPP1LMNAMAPK1TK1 | |
| SCHEMBL7219926 | 0.81 | MAPK1 (0.54) | TYMPMAPK1TK1HPGD | |
| SCHEMBL1834796 | 0.80 | UPP1 (0.57) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL6372044 | 0.79 | LMNA (0.56) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL13321360 | 0.79 | CYP1A2 (0.48) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL1287949 | 0.77 | HTT (0.36) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL7219565 | 0.76 | TK2 (0.41) | CYP1A2BLMUPP1MAPK1TK1 | |
| SCHEMBL7219562 | 0.76 | TK2 (0.41) | CYP1A2BLMUPP1MAPK1TK1 | |
| SCHEMBL9885886 | 0.76 | HPGD (0.35) | KMT2ACYP1A2UPP1LMNAMAPK1 | |
| SCHEMBL11370922 | 0.76 | KMT2A (0.62) | KMT2AHSD17B10UPP1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37979-E1 | Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof | MITSUBISHI CHEMICAL CORPORATION | 2003-02-04 | — | — | US | disclosed |
| EP-0829476-B1 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | MITSUBISHI CHEM CORP (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-0829476-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5461060-A | Antiretroviral activity | MITSUBISHI KASEI CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0420763-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1991-04-03 | — | — | EP | disclosed |