Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | DUT | P33316 | 10/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711032 | 0.84 | PKM (0.58) | PKMDUTENPP1CRBN | |
| SCHEMBL11583672 | 0.84 | PKM (0.44) | PKMDUTENPP1CRBN | |
| SCHEMBL9885885 | 0.83 | PKM (0.32) | PKMDUT | |
| SCHEMBL8656960 | 0.80 | PKM (0.45) | PKMDUTCRBN | |
| SCHEMBL41240 | 0.77 | PKM (0.42) | PKMDUTCRBN | |
| SCHEMBL17295676 | 0.76 | PKM (0.43) | PKMDUTCRBN | |
| SCHEMBL9354274 | 0.75 | DUT (0.81) | DUTENPP1 | |
| SCHEMBL11546247 | 0.75 | DUT (0.41) | PKMDUTCRBN | |
| SCHEMBL5792152 | 0.74 | CRBN (0.42) | PKMDUTENPP1CRBN | |
| SCHEMBL16671885 | 0.73 | HTT (0.41) | PKMDUTCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37979-E1 | Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof | MITSUBISHI CHEMICAL CORPORATION | 2003-02-04 | — | — | US | disclosed |
| EP-0829476-B1 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | MITSUBISHI CHEM CORP (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-0829476-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5461060-A | Antiretroviral activity | MITSUBISHI KASEI CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0420763-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1991-04-03 | — | — | EP | disclosed |