SCHEMBL5792152

SCHEMBL5792152

NCn1ccc(=O)[nH]c1=S

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.42
PKM P14618 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
TP53 P04637 1/20 0.34
DDB1 Q16531 1/20 0.34
DUT P33316 4/20 0.34
ENPP1 P22413 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8656960 0.82 PKM (0.45) CRBNPKML3MBTL1ALDH1A1LMNA
SCHEMBL11581000 0.79 ALDH1A1 (0.43) CRBNPKML3MBTL1ALDH1A1LMNA
SCHEMBL41240 0.79 PKM (0.42) CRBNPKML3MBTL1DUT
SCHEMBL6102943 0.78 CRBN (0.56) CRBNPKML3MBTL1ALDH1A1LMNA
SCHEMBL7752441 0.77 PKM (0.38) CRBNPKML3MBTL1ALDH1A1LMNA
SCHEMBL9426408 0.77 ALDH1A1 (0.40) PKMALDH1A1DUT
SCHEMBL1673256 0.77 KMT2A (0.42) PKML3MBTL1ALDH1A1LMNADUT
SCHEMBL4278691 0.77 PKM (0.38) CRBNPKML3MBTL1ALDH1A1LMNA
Glycine SCHEMBL2322499 0.76 DUT (0.39) CRBNPKMALDH1A1LMNADUT
SCHEMBL2284397 0.76 DBH (0.57) ALDH1A1MTNR1AMTNR1BTP53DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116390748-A Compositions for preventing and treating influenza infection and methods of use thereof 佐治亚大学研究基金会股份有限公司 2023-07-04 CN disclosed
CN-110506119-A The design of AAV capsid UNIV MASSACHUSETTS 2019-11-26 CN disclosed
CN-110456035-A Probing analysis and its application based on cell BERG LLC 2019-11-15 CN disclosed
CN-110042099-A RNA in skin and fibrotic conditions is interfered 菲奥医药公司 2019-07-23 CN disclosed
CN-104822705-B M971 Chimeric antigen receptor 美国卫生和人力服务部 2019-07-12 CN disclosed
CN-106471133-B Mononucleotide detection method 贝斯4创新公司 2019-07-09 CN disclosed
CN-105378109-B Minimizing errors using uracil-DNA-N-glycosylase 雅培分子公司 2019-06-14 CN disclosed
CN-109790211-A Anti-KRAS-G12D T cell receptor 美国卫生和人力服务部 2019-05-21 CN disclosed
CN-105131067-B RNA in skin and fibrotic conditions is interfered 雷克西制药公司 2019-02-19 CN disclosed
CN-105246507-B VISTA Modulators for Diagnosis and Treatment of Cancer 达特茅斯大学理事会 2019-01-25 CN disclosed
CN-1407900-A Method for treating or preventing cell, tissue, and organ damage using human bone marrow progenitor cell inhibitory factor-1 (MPIF-1) HUMAN GENOME SCIENCES INC (US) 2003-04-02 CN disclosed
CN-1398300-A Novel elongase gene and method for producing polyunsaturated fatty acids BASF AG (DE) 2003-02-19 CN disclosed
CN-1392797-A High mannose proteins and methods of producing high mannose proteins TRANSKARYOTIC THERAPIES INC (US) 2003-01-22 CN disclosed
CN-1372569-A Keratinocyte growth factor-2 HUMAN GENOME SCIENCES INC (US) 2002-10-02 CN disclosed
CN-1354755-A Nucleotide and protein sequences of Nogo genes and methods based thereon SCHWAB MARTIN E (CH) 2002-06-19 CN disclosed
CN-1346368-A Potassium channel interactors and uses therefor MILLENNIUM PHARM INC (US) 2002-04-24 CN disclosed
CN-1342208-A Method for manipulating complex nucleic acid populations using peptide-labeled oligonucleotides VALIGENE CORP (US) 2002-03-27 CN disclosed
CN-1312372-A Intocostrin regulation area and nucleotide series determination and method used thereof PFIZER PRODUCTS CORP (US) 2001-09-12 CN disclosed
CN-1211255-A Ob receptor and method of diagnosing and treating weight MILLENNIUM PHARM INC (US) 1999-03-17 CN disclosed
CN-1171112-A Amino acid nucleic acids ICN PHARMACEUTICALS CO (US) 1998-01-21 CN disclosed