Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TTK | P33981 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715965 | 0.86 | ALOX15 (0.38) | ALOX15KDM4EALDH1A1HPGDGAA | |
| SCHEMBL4975817 | 0.83 | TDP1 (0.41) | ALOX15KDM4EALDH1A1HPGDGAA | |
| SCHEMBL2877031 | 0.83 | ALOX15 (0.39) | ALOX15KDM4EALDH1A1HPGDGAA | |
| SCHEMBL544849 | 0.83 | CSNK1A1 (0.45) | ALOX15KDM4EALDH1A1HPGDGAA | |
| SCHEMBL544426 | 0.83 | KDM4E (0.47) | ALOX15KDM4EALDH1A1HPGDGAA | |
| SCHEMBL9451310 | 0.83 | MEN1 (0.41) | ALOX15KDM4EALDH1A1HPGDGAA | |
| SCHEMBL18727625 | 0.79 | LMNA (0.56) | ALOX15KDM4EALDH1A1HPGDGAA | |
| SCHEMBL715964 | 0.79 | ALOX15 (0.33) | ALOX15KDM4EALDH1A1HPGDGAA | |
| SCHEMBL20033942 | 0.78 | KDM4E (0.41) | ALOX15KDM4EALDH1A1HPGDGAA | |
| SCHEMBL10338995 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461327-A | Diagnoses and treatment reagent | UNIV HONG KONG SCIENCE & TECH | 2019-11-15 | — | — | CN | disclosed |
| US-6620940-B1 | Heterocyclic nitrogen/sulfur compounds used as chemical intermediates for drugs such as 3-chloro-4-(furan-2-yl)-1,2,5 -thiadiazole | ELI LILLY AND COMPANY | 2003-09-16 | — | — | US | disclosed |
| EP-0948592-A2 | THIADIAZOLE DIOXIDE DERIVED OXAZIRIDINES AS BLEACHING COMPOUNDS | UNILEVER N.V. (NL) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998024877-A2 | THIADIAZOLE DIOXIDE DERIVED OXAZIRIDINES AS BLEACHING COMPOUNDS | UNILEVER N.V. (NL) | 1998-06-11 | — | — | WO | disclosed |