SCHEMBL7213739

SCHEMBL7213739

COc1ccc2c(c1)C=CC(c1ccccc1)(c1ccccc1)O2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
GAA P10253 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
PLIN1 O60240 1/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.46
PKM P14618 1/20 0.46
TSHR P16473 1/20 0.46
RECQL P46063 1/20 0.46
PLIN5 Q00G26 1/20 0.46
ABHD5 Q8WTS1 1/20 0.46
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
HIF1A Q16665 3/20 0.41
EPAS1 Q99814 3/20 0.41
PPIB P23284 1/20 0.40
HTR2C P28335 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26780650 0.82 LTA4H (0.50) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL25968633 0.80 CES2 (0.43) MAPTMEN1KMT2AGAALMNA
SCHEMBL7131287 0.80 KDM4E (0.40) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL5264237 0.79 CYP1A2 (0.41) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL20848051 0.77 CA12 (0.39) MAPTMEN1KMT2AGAATDP1
SCHEMBL2009830 0.76 HIF1A (0.52) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL8871056 0.76 HTR2C (0.46) MAPTMEN1KMT2ATSHRHTR2C
SCHEMBL28216646 0.75 CA9 (0.46) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL2134543 0.74 CYP11B1 (0.41) MAPTMEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL7126396 0.74 CYP1A2 (0.36) MAPTGAASMN1; SMN2TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10147776-A None JP disclosed
US-20030140934-A1 Wig for decorating hair ADERANS CO., LTD. (JP) 2003-07-31 US disclosed
EP-1275314-A1 WIG FOR DECORATING HAIR ADERANS CO., LTD. (JP) 2003-01-15 EP disclosed
JP-H10147776-A PHOTOCHROMIC COMPOSITION MATSUI SHIKISO KAGAKU KOGYOSHO:KK 1998-06-02 JP disclosed