SCHEMBL25968633

SCHEMBL25968633

COc1ccc(C2(c3ccc(OC)cc3)C=Cc3cc(C(=O)c4ccccc4)ccc3O2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
HPGD P15428 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C19 P33261 2/20 0.42
ALDH1A1 P00352 2/20 0.42
GAA P10253 1/20 0.42
ELANE P08246 2/20 0.42
STS P08842 2/20 0.41
MAPK1 P28482 3/20 0.40
MAPT P10636 3/20 0.40
KMT2A Q03164 3/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
ACHE P22303 1/20 0.40
LMNA P02545 3/20 0.40
PGR P06401 1/20 0.40
SLC6A2 P23975 1/20 0.40
PDE4A P27815 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7213739 0.80 MAPT (0.46) HPGDCYP1A2ALDH1A1GAAMAPT
SCHEMBL25973992 0.78 SMN1; SMN2 (0.47) HPGDALDH1A1MAPK1MAPTKMT2A
SCHEMBL482234 0.76 COXFA4 (0.49) HPGDALDH1A1ELANEMAPTRAB9A
SCHEMBL27100790 0.72 SMN1; SMN2 (0.42) CES2CES1HPGDCYP1A2CYP2D6
SCHEMBL28728499 0.72 CES2 (0.71) CES2CES1HPGDCYP1A2CYP2D6
SCHEMBL50261 0.72 CES2 (0.77) CES2CES1HPGDCYP1A2CYP2D6
Benzophenone SCHEMBL27935236 0.72 CES2 (0.77) CES2CES1HPGDCYP1A2CYP2D6
SCHEMBL6618691 0.72 CES2 (0.77) CES2CES1HPGDCYP1A2CYP2D6
SCHEMBL25973503 0.72 KMT2A (0.58) HPGDCYP1A2CYP2D6CYP2C19ALDH1A1
SCHEMBL28938917 0.71 CES2 (0.69) CES2CES1HPGDCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed
EP-4282655-A2 PROCESS AND APPARATUS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION AND METHOD FOR VOLUMETRIC PRINTING OF A SHAPED BODY xolo GmbH (DE) 2023-11-29 EP disclosed
EP-4224253-B1 PROCESS, APPARATUS AND PHOTOSWITCHABLE PHOTOINITIATORS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION AND METHOD FOR VOLUMETRIC PRINTING OF A SHAPED BODY XOLO GMBH (DE) 2023-11-15 EP disclosed
EP-4224253-A2 PROCESS, APPARATUS AND PHOTOSWITCHABLE PHOTOINITIATORS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION AND METHOD FOR VOLUMETRIC PRINTING OF A SHAPED BODY Xolo GmbH (DE) 2023-08-09 EP disclosed