Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16196568 | 0.89 | NNMT (0.45) | NNMTHTR2AHTR2CHTR2B | |
| SCHEMBL12605346 | 0.78 | NNMT (0.55) | NNMTNOTUMPARP10PARP11GRM5 | |
| SCHEMBL7213850 | 0.78 | NNMT (0.55) | NNMTPARP10PARP11GRM5 | |
| SCHEMBL13991574 | 0.75 | PARP10 (0.42) | NNMTHTR2AHTR2CHTR2BNOTUM | |
| SCHEMBL13343936 | 0.71 | NNMT (0.73) | NNMTNOTUM | |
| SCHEMBL13359524 | 0.70 | CHRNB2 (0.36) | NNMTHTR2AHTR2CHTR2BNOTUM | |
| SCHEMBL21921376 | 0.70 | NNMT (0.41) | NNMT | |
| SCHEMBL16195616 | 0.68 | NNMT (0.45) | NNMT | |
| SCHEMBL3803152 | 0.67 | NNMT (0.44) | NNMTHTR2AHTR2CHTR2BNOTUM | |
| SCHEMBL29487134 | 0.67 | NNMT (0.44) | NNMTHTR2AHTR2CHTR2BNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465726-B2 | Substituted pyrrolo[2.3-B]pyridines | OSI PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |