Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789136 | 0.82 | LTA4H (0.42) | USP2RAB9ALTA4HCYP19A1CYP11B1 | |
| SCHEMBL7216749 | 0.81 | LOXL2 (0.38) | USP2RAB9ALTA4HCYP19A1IDO1 | |
| SCHEMBL7220974 | 0.78 | DPP4 (0.38) | USP2RAB9ALTA4HCYP19A1IDO1 | |
| SCHEMBL8919343 | 0.77 | USP2 (0.39) | USP2RAB9ALTA4HCYP19A1CYP11B1 | |
| SCHEMBL7221278 | 0.75 | KMT2A (0.35) | USP2RAB9ALTA4HCYP19A1CYP11B1 | |
| SCHEMBL23882924 | 0.74 | CYP19A1 (0.59) | USP2RAB9ALTA4HCYP19A1CYP11B1 | |
| SCHEMBL29173225 | 0.74 | MAPKAPK2 (0.45) | USP2RAB9ALTA4HCYP19A1MAPK14 | |
| SCHEMBL3061844 | 0.74 | USP2 (0.47) | USP2RAB9ALTA4HCYP19A1CYP11B1 | |
| SCHEMBL30599784 | 0.74 | CYP19A1 (0.45) | USP2RAB9ALTA4HCYP19A1CYP11B1 | |
| SCHEMBL11196968 | 0.74 | CYP19A1 (0.59) | USP2RAB9ALTA4HCYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630485-B2 | For therapy of inflammatory disease | SYNTEX (U.S.A.) LLC | 2003-10-07 | — | — | US | disclosed |
| US-6479507-B2 | MODULATION OF THESE INFLAMMATORY CYTOKINES IS CONSIDERED ONE OF THE MOST EFFECTIVE STRATEGIES TO BLOCK CHRONIC INFLAMMATION AND HAVE POSITIVE THERAPEUTIC OUTCOMES | SYNTEX (U.S.A.) LLC | 2002-11-12 | — | — | US | disclosed |
| US-6316464-B1 | P38 MAP kinase inhibitors | SYNTEX (U.S.A.) LLC | 2001-11-13 | — | — | US | disclosed |