Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215162 | 0.94 | KDR (0.54) | ALDH1A1KDRKCNH3MEN1KMT2A | |
| SCHEMBL1431624 | 0.86 | MEN1 (0.53) | ALDH1A1KDRKCNH3MEN1KMT2A | |
| SCHEMBL6231348 | 0.81 | ABL1 (0.49) | ALDH1A1KCNH3MEN1KMT2AHPGD | |
| SCHEMBL11119734 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL12355294 | 0.80 | MEN1 (0.55) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL19968723 | 0.80 | ABL1 (0.51) | ALDH1A1KCNH3MEN1KMT2AHPGD | |
| SCHEMBL2537295 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KCNH3MEN1KMT2AHPGD | |
| SCHEMBL10581290 | 0.80 | MAPT (0.69) | ALDH1A1KCNH3MEN1KMT2AHPGD | |
| SCHEMBL11935735 | 0.80 | MAPT (0.44) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL7649344 | 0.80 | ABL1 (0.51) | ALDH1A1KCNH3MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630485-B2 | For therapy of inflammatory disease | SYNTEX (U.S.A.) LLC | 2003-10-07 | — | — | US | disclosed |
| US-6316464-B1 | P38 MAP kinase inhibitors | SYNTEX (U.S.A.) LLC | 2001-11-13 | — | — | US | disclosed |