SCHEMBL7214767

SCHEMBL7214767

[c]1cccc2c1N(c1ccccc1)c1ccccc1S2

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.44
MAOA P21397 1/20 0.40
NOX1 Q9Y5S8 1/20 0.39
BCHE P06276 11/20 0.37
ACHE P22303 4/20 0.37
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.35
HTR1A P08908 1/20 0.33
ADRB3 P13945 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
DRD3 P35462 1/20 0.33
HTR2B P41595 1/20 0.33
HTR6 P50406 1/20 0.33
KDM1A O60341 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387100 0.84 HDAC6 (0.56) HDAC6MAOANOX1BCHEACHE
SCHEMBL342426 0.84 HDAC6 (0.56) HDAC6MAOANOX1BCHEACHE
SCHEMBL12190901 0.78 HDAC6 (0.62) HDAC6MAOANOX1BCHEACHE
SCHEMBL29851224 0.78 HDAC6 (0.62) HDAC6MAOANOX1BCHEACHE
SCHEMBL2804853 0.76 MAOA (0.62) MAOANOX1BCHEMEN1LMNA
SCHEMBL3794995 0.76 NOX1 (0.44) HDAC6MAOANOX1BCHEACHE
SCHEMBL21409893 0.75 HDAC6 (0.45) HDAC6MAOANOX1BCHEACHE
SCHEMBL9776392 0.75 HDAC6 (0.45) HDAC6MAOANOX1BCHEACHE
SCHEMBL712954 0.74 HDAC6 (0.51) HDAC6MAOANOX1BCHEACHE
SCHEMBL29384924 0.74 HDAC6 (0.47) HDAC6MAOANOX1BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256447-A Indoles simultaneously [3,2,1-jk] carbazole derivates, preparation method and application and electronic device 苏州大学 2019-09-20 CN claimed
US-11939341-B2 Organic compound, electroluminescent material, and application thereof WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2024-03-26 US disclosed
CN-111704624-B Indolo [3,2,1-kl ] phenoxazine compounds, preparation method and application thereof, and electronic device 苏州大学 2023-04-04 CN disclosed
US-20210147442-A1 ORGANIC COMPOUND, ELECTROLUMINESCENT MATERIAL, AND APPLICATION THEREOF WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2021-05-20 US disclosed
CN-111704624-A Indolo [3,2,1-kl ] phenoxazine compound, preparation method and application thereof, and electronic device 苏州大学 2020-09-25 CN disclosed
US-6617053-B2 High luminous efficiency and a long life CHISSO CORPORATION (JP) 2003-09-09 US disclosed
US-20020027415-A1 Organic electroluminescent device containing dithiafulvene derivative CHISSO CORPORATION (JP) 2002-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147442-A1 ORGANIC COMPOUND, ELECTROLUMINESCENT MATERIAL, AND APPLICATION THEREOF ILK, OSTC, LEF1 HDAC6 4336/4885MAOA 1429/4885NOX1 683/4885
US-11939341-B2 Organic compound, electroluminescent material, and application thereof ILK, OSTC, LEF1 HDAC6 4336/4885MAOA 1429/4885NOX1 683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.