Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331695 | 1.00 | PDE4A (0.49) | PDE4APDE4BPDE4DPDE4CRECQL | |
| SCHEMBL7332199 | 0.88 | PDE4A (0.55) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7332185 | 0.88 | PDE4A (0.55) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7329994 | 0.82 | POLB (0.55) | PDE4APDE4BPDE4DPDE4CRECQL | |
| SCHEMBL7333339 | 0.81 | PDE4B (0.47) | PDE4APDE4BPDE4DPDE4CRECQL | |
| SCHEMBL7333351 | 0.81 | PDE4B (0.47) | PDE4APDE4BPDE4DPDE4CRECQL | |
| Nitrous Acid SCHEMBL7214855 | 0.81 | PDE4B (0.54) | PDE4APDE4BPDE4DPDE4CRECQL | |
| SCHEMBL3976102 | 0.80 | PDE4B (0.57) | PDE4APDE4BPDE4DPDE4CRECQL | |
| SCHEMBL2371289 | 0.79 | PDE4B (0.60) | PDE4APDE4BPDE4DPDE4CRECQL | |
| SCHEMBL2958828 | 0.78 | RECQL (0.60) | PDE4APDE4BPDE4DPDE4CRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470805-B1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PROD (US) | 1994-09-07 | — | — | EP | claimed |
| EP-0470805-A1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-02-12 | — | — | EP | claimed |