Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.54 |
| ▸ | PDE4A | P27815 | 10/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332241 | 0.87 | PDE4A (0.57) | PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL2371289 | 0.86 | PDE4B (0.60) | POLBPDE4BPDE4APDE4DPDE4C | |
| SCHEMBL7332617 | 0.85 | PDE4B (0.58) | POLBPDE4BPDE4APDE4DPDE4C | |
| SCHEMBL7023339 | 0.85 | PDE4B (0.55) | POLBPDE4BPDE4APDE4DPDE4C | |
| SCHEMBL7364116 | 0.85 | PDE4B (0.56) | POLBPDE4BPDE4APDE4DPDE4C | |
| SCHEMBL7340266 | 0.83 | PDE4B (0.53) | POLBPDE4BPDE4APDE4DPDE4C | |
| SCHEMBL8373034 | 0.83 | LMNA (0.58) | — | |
| SCHEMBL31618757 | 0.83 | LMNA (0.58) | — | |
| SCHEMBL7331685 | 0.82 | PDE4A (0.49) | POLBPDE4BPDE4APDE4DPDE4C | |
| SCHEMBL7331695 | 0.82 | PDE4A (0.49) | POLBPDE4BPDE4APDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470805-A1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-02-12 | — | — | EP | claimed |