Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2430704 | 0.66 | — | — | |
| SCHEMBL13518881 | 0.63 | LMNA (0.43) | LMNAALOX15BLMPMP22 | |
| SCHEMBL1169223 | 0.63 | — | — | |
| SCHEMBL27488352 | 0.63 | GAA (0.30) | LMNAALOX15BLMPMP22GAA | |
| SCHEMBL18691971 | 0.63 | TDP1 (0.30) | LMNAALOX15BLMPMP22GAA | |
| SCHEMBL29145 | 0.61 | — | — | |
| SCHEMBL17065142 | 0.61 | LMNA (0.33) | LMNAALOX15BLMPMP22GAA | |
| SCHEMBL10797506 | 0.61 | LMNA (0.33) | LMNAALOX15BLMPMP22GAA | |
| SCHEMBL27738297 | 0.60 | — | — | |
| SCHEMBL7980141 | 0.58 | LMNA (0.46) | LMNAALOX15BLMPMP22GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599890-B1 | Inhibitors of matrix metalloproteinases or the production of tumor necrosis factor | PFIZER INC | 2003-07-29 | — | — | US | disclosed |
| EP-0960098-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998034918-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-08-13 | — | — | WO | disclosed |