Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644662 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL10532393 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL622968 | 0.67 | LMNA (0.31) | LMNA | |
| SCHEMBL9865292 | 0.67 | ALDH1A1 (0.37) | — | |
| SCHEMBL21327778 | 0.67 | DGAT1 (0.33) | LMNA | |
| SCHEMBL2400907 | 0.65 | CES1 (0.48) | — | |
| SCHEMBL25204077 | 0.65 | GLRA1 (0.32) | — | |
| SCHEMBL28642028 | 0.65 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL31529621 | 0.65 | — | — | |
| SCHEMBL27758606 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135782-B | Dental composition | 登特斯普伊德特雷有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-108135781-B | Dental composition | 登特斯普伊德特雷有限公司 | 2021-04-16 | — | — | CN | disclosed |
| US-10588830-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2020-03-17 | — | — | US | disclosed |
| EP-3359118-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2020-01-29 | — | — | EP | disclosed |
| US-20180303722-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2018-10-25 | — | — | US | disclosed |
| US-20180289592-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2018-10-11 | — | — | US | disclosed |
| WO-2017060527-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-04-13 | — | — | WO | disclosed |
| WO-2017060459-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-04-13 | — | — | WO | disclosed |
| EP-3153150-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2017-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180289592-A1 | DENTAL COMPOSITION | AP2M1, CAD, ERAL1 | TDP1 2811/4885GAA 1711/4885LMNA 1338/4885 |
| US-10588830-B2 | Dental composition | CAD, ALG8, KATNAL2 | TDP1 2161/4885GAA 862/4885LMNA 2076/4885 |
| US-20180303722-A1 | DENTAL COMPOSITION | CAD, ALG8, KATNAL2 | TDP1 2161/4885GAA 862/4885LMNA 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.