Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.52 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18111494 | 0.79 | CHRNB2 (0.54) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL6577750 | 0.76 | P2RY14 (0.59) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL5194310 | 0.73 | CHRNB2 (0.51) | CHRNB2CHRNA4P2RY14SLC6A3 | |
| SCHEMBL5194296 | 0.73 | CHRNB2 (0.51) | CHRNB2CHRNA4P2RY14SLC6A3 | |
| SCHEMBL7210356 | 0.73 | CHRNB2 (0.45) | CHRNB2CHRNA4P2RY14 | |
| SCHEMBL6575446 | 0.73 | CHRNB2 (0.45) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL7216173 | 0.70 | CHRNB2 (0.68) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| Malonic Acid SCHEMBL5193537 | 0.70 | CHRNB2 (0.45) | CHRNB2CHRNA4P2RY14SLC6A4SLC6A3 | |
| SCHEMBL34471162 | 0.70 | SLC6A3 (0.55) | SLC6A3HRH2HRH1HRH3MMP3 | |
| SCHEMBL1023383 | 0.70 | CHRNB2 (0.48) | CHRNB2CHRNA4P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010047028-A1 | Novel azabicyclo derivatives and their use | ANIONA APS (DK) | 2001-11-29 | — | — | US | claimed |
| EP-1149095-A1 | NOVEL AZABICYCLO DERIVATIVES AND THEIR USE | NEUROSEARCH A/S (DK) | 2001-10-31 | — | — | EP | claimed |
| WO-2000044746-A1 | NOVEL AZABICYCLO DERIVATIVES AND THEIR USE | NEUROSEARCH A/S (DK) | 2000-08-03 | — | — | WO | claimed |
| US-6617459-B2 | 8-azabicyclo(3.2.1)oct-2-ene and 9-azabicyclo(3.3.1)non-2-ene derivatives; monoamine neurotransmitter and serotonine reuptake inhibitors; radionuclide-labeled derivatives for diagnosis and detection | NEUROSEARCH A/S (DK) | 2003-09-09 | — | — | US | disclosed |
| US-20010047028-A1 | Novel azabicyclo derivatives and their use | ANIONA APS (DK) | 2001-11-29 | — | — | US | disclosed |
| EP-1149095-A1 | NOVEL AZABICYCLO DERIVATIVES AND THEIR USE | NEUROSEARCH A/S (DK) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000044746-A1 | NOVEL AZABICYCLO DERIVATIVES AND THEIR USE | NEUROSEARCH A/S (DK) | 2000-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047028-A1 | Novel azabicyclo derivatives and their use | TACR2, TACR3, GPR68 | CHRNB2 66/4885CHRNA4 117/4885P2RY14 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.