Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3275756 | 0.81 | PAX8 (0.44) | PAX8ALDH1A1HSD17B10MAOAMAOB | |
| SCHEMBL15732920 | 0.73 | ALDH1A1 (0.43) | PAX8ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL5100540 | 0.71 | PAX8 (1.00) | PAX8ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL11301205 | 0.71 | PAX8 (0.46) | PAX8ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL20783635 | 0.71 | ALDH1A1 (0.42) | PAX8ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL8856454 | 0.69 | ALDH1A1 (0.46) | PAX8ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL1133100 | 0.69 | KDM4E (0.48) | ALDH1A1HSD17B10HPGDKDM4EGLA | |
| SCHEMBL927812 | 0.67 | ALDH1A1 (0.50) | PAX8ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL4311602 | 0.67 | — | — | |
| SCHEMBL5316204 | 0.67 | ALDH1A1 (0.39) | PAX8ALDH1A1HSD17B10TDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6621098-B1 | Thin-film transistor and methods of manufacturing and incorporating a semiconducting organic material | THE PENN STATE RESEARCH FOUNDATION | 2003-09-16 | — | — | US | claimed |
| CN-104736700-A | Compositions and methods comprising lipolytic enzyme variants | DANISCO US INC | 2015-06-24 | — | — | CN | disclosed |
| US-6621098-B1 | Thin-film transistor and methods of manufacturing and incorporating a semiconducting organic material | THE PENN STATE RESEARCH FOUNDATION | 2003-09-16 | — | — | US | disclosed |