Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | CFB | P00751 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220601 | 0.78 | GRM2 (0.41) | KMT2AKDM4EPRCP | |
| SCHEMBL7216865 | 0.78 | ACHE (0.43) | KMT2AMEN1USP2TSHRNPSR1 | |
| SCHEMBL7220444 | 0.75 | PRCP (0.41) | USP2TSHRNPSR1PRCP | |
| SCHEMBL7215357 | 0.73 | PRCP (0.40) | KMT2AMEN1USP2TSHRNPSR1 | |
| SCHEMBL7214547 | 0.73 | MAOB (0.39) | KMT2AMEN1USP2TSHRNPSR1 | |
| SCHEMBL7216729 | 0.70 | ACHE (0.48) | NPSR1PRCP | |
| SCHEMBL7217023 | 0.69 | ACHE (0.49) | NPSR1 | |
| SCHEMBL7216927 | 0.69 | KDM4E (0.49) | ALDH1A1KDM4EPRCP | |
| SCHEMBL25881974 | 0.68 | MEN1 (0.47) | KMT2AMEN1SPHK2SPHK1ALDH1A1 | |
| SCHEMBL25685938 | 0.67 | SPHK2 (0.61) | KMT2AMEN1SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630485-B2 | For therapy of inflammatory disease | SYNTEX (U.S.A.) LLC | 2003-10-07 | — | — | US | disclosed |