Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216865 | 0.80 | ACHE (0.43) | LMNASLC6A4SLC6A3SLC6A2MEN1 | |
| SCHEMBL7215357 | 0.80 | PRCP (0.40) | SLC6A3PRCPMEN1KMT2ACYP3A4 | |
| SCHEMBL7220444 | 0.77 | PRCP (0.41) | SLC6A3PRCPUSP2TSHRNPSR1 | |
| SCHEMBL7215286 | 0.73 | KMT2A (0.46) | PRCPMEN1KMT2APKMUSP2 | |
| SCHEMBL7216927 | 0.72 | KDM4E (0.49) | LMNASLC6A3PRCPCYP3A4CYP2C19 | |
| SCHEMBL7214446 | 0.71 | NPC1 (0.38) | SLC6A3PRCPMEN1KMT2ANPSR1 | |
| SCHEMBL7220601 | 0.71 | GRM2 (0.41) | MAOBLMNAPRCPKMT2A | |
| SCHEMBL7216729 | 0.70 | ACHE (0.48) | LMNASLC6A3PRCPCYP3A4NPSR1 | |
| SCHEMBL7217023 | 0.69 | ACHE (0.49) | LMNASLC6A3CYP3A4NPSR1 | |
| SCHEMBL7216749 | 0.63 | LOXL2 (0.38) | SLC6A3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630485-B2 | For therapy of inflammatory disease | SYNTEX (U.S.A.) LLC | 2003-10-07 | — | — | US | disclosed |