Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15275621 | 1.00 | ADRB1 (0.66) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL19944672 | 0.90 | ADRB1 (0.73) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL9599229 | 0.86 | ADRB1 (0.68) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL18034999 | 0.86 | ADRB2 (0.68) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL9598039 | 0.86 | ADRB1 (0.68) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL11857860 | 0.85 | ADRB1 (0.49) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL11093561 | 0.84 | ADRB2 (0.66) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL12122747 | 0.83 | ADRB1 (0.68) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| Hydrochloric Acid SCHEMBL10607565 | 0.83 | ADRB2 (0.64) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL6277059 | 0.82 | ADRB1 (0.67) | ADRB1ADRB2CYP2D6NR3C1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247642-A1 | SYNTHESIS AND PREPARATIONS OF METOPROLOL AND ITS SALTS | MEDINCO S.P.A. (IT) | 2009-10-01 | — | — | US | disclosed |
| US-20090247642-A1 | SYNTHESIS AND PREPARATIONS OF METOPROLOL AND ITS SALTS | MEDINCO S.P.A. (IT) | 2009-10-01 | — | — | US | disclosed |
| EP-0942899-B1 | MANUFACTURING PROCESS OF METOPROLOL | ASTRAZENECA AB (SE) | 2003-03-12 | — | — | EP | disclosed |
| US-5082969-A | Industrial process for obtaining an aryloxypropanolamine | ESTEVE QUIMICA, S.A. (ES) | 1992-01-21 | — | — | US | disclosed |
| US-5082969-A | Industrial process for obtaining an aryloxypropanolamine | ESTEVE QUIMICA, S.A. (ES) | 1992-01-21 | — | — | US | disclosed |
| US-3998790-A | PHENOXY-HYDROXYPROPYLAMINES, THEIR PREPARATION, AND METHOD AND PHARMACEUTICAL PREPARATIONS FOR TREATING CARDIOVASCULAR DISEASES | AKTIEBOLAGET HASSLE (SW) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247642-A1 | SYNTHESIS AND PREPARATIONS OF METOPROLOL AND ITS SALTS | ADRB1, ADRB3, ADRB2 | ADRB1 1/4885ADRB2 3/4885CYP2D6 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.